the Altmetric Attention Score and how the score is calculated. Xue Sun, Hansen Yang, Zhimiao Wang, Fang Li, Hualiang An, Wei Xue. Solubility of 4-Methylsulfonylacetophenone in Nine Pure Solvents and (Ethyl Acetate + n-Hexane) Binary Solvent Mixtures from 278.15 K to 328.15 K. Baptiste Bouillot, Sébastien Teychené, and Béatrice Biscans . [16] It fluoresces in the blue at 420 nm. Brown, Juliet A. Adelakun, Xiong-wei Ni. Phase Equilibria of the System Drug + Water. Low-cost system based on image analysis to determine solubility curves. Zilin Meng, Fengzhu Lv, Yihe Zhang, Qian Zhang, Zhilei Zhang, Shutao Ai. It has the formula C7H6O3. Thermodynamics of fenoxycarb in solution. Controllable synthesis of Bi2S3 via a simple hydrothermal approach starting from an inorganic precursor. Gajanand Sharma, Neelam Devi, Kanika Thakur, Ashay Jain, OP Katare. Dawn M. Stovall, Amber Schmidt, Colleen Dai, Shoshana Zhang, William E. Acree, Michael H. Abraham. Engineering cocrystal solubility, stability, and pHmax by micellar solubilization. These metrics are regularly updated to reflect usage leading up to the last few days. Berkant Kayan, Yu Yang, Edward J. Lindquist and A. Murat Gizir . Salicylate's antirheumatic (nonsteroidal anti-inflammatory) actions are a result of its analgesic and anti-inflammatory mechanisms. In addition to serving as an important active metabolite of aspirin (acetylsalicylic acid), which acts in part as a prodrug to salicylic acid, it is probably best known for its use as a key ingredient in topical anti-acne products. Pro, Vedantu Salicylic acid is also used to treat a very rare genetic skin disorder, named Ichthyosis, in which skin becomes dry, scaly and thick. [38] Salicylic acid is involved in endogenous signaling, mediating in plant defense against pathogens. Salicylic acid inhibits the oxidation of uridine-5-diphosphoglucose (UDPG) competitively with nicotinamide adenosine dinucleotide (NAD) and noncompetitively with UDPG. Prediction of aqueous solubilities of solid carboxylic acids with COSMO-RS. • Salicylic acid also helps in the removal of blackheads and whiteheads. It is easily prepared on a clean surface by spraying a saturated solution of the salt in methanol followed by evaporation. Prediction of solubility curves and melting properties of organic and pharmaceutical compounds. Details. Industrial & Engineering Chemistry Research. Joseph Nti-Gyabaah, Kodzo Gbewonyo, and Yee C. Chiew . Solubility of salicylic acid in pure alcohols at different temperatures. [20], Salicylic acid has the formula C6H4(OH)COOH, where the OH group is ortho to the carboxyl group. It does not let the skin pores clog and the ones that are already clogged can be opened by the application of salicylic acid over that particular area. The melting point determination apparatus is filled with paraffin and fitted with a thermometer. Measurement of solubility of mitomycin C in ethanol–water solutions at different temperatures. It was first derived from the bark of Willow Tree. Erin Hart, Damini Grover, Heidi Zettl, Victoria Koshevarova, William E. Acree, Michael H. Abraham. Salicylic Acid exist as clear white or colourless and odourless needle-shaped crystals at room temperature. The Altmetric Attention Score is a quantitative measure of the attention that a research article has received online. The creation and testing of a fully continuous tubular crystallization device suited for incorporation into flow chemistry setups. Santos, Isabel M. Marrucho, João A.P. In aspirin (assuming you mean the pure compound and not the tablet with the other parts of the formulation), the hydroxyl group is part of an ester of acetic acid. A higher solubility was related to a lower van't Hoff enthalpy of solution. Evaluation of Multipoint Dosing Strategy in a Miniaturized Tubular Reactor: Nitration of Salicylic Acid. However, it is advised by the health agencies do not use salicylic acid medications on genital warts or warts containing hair growths. José Rodrigo Vergara-Salinas, José Cuevas-Valenzuela, José R. Pérez-Correa. Thermodynamics and crystallization of a theophylline–salicylic acid cocrystal. Several studies suggest that humans metabolize salicylic acid in measurable quantities from these plants. Assessing the Salting-Out Behavior of Nitrobenzene, 2-Nitrotoluene, and 3-Nitrotoluene from Solubility Values in Pure Water and Seawater at Temperatures between (277 and 314) K. António J. Queimada, Fátima L. Mota, Simão P. Pinho and Eugénia A. Macedo . European Journal of Pharmaceutical Sciences. Salicylic Acid, USP-AHA-SAAC-01. The European Physical Journal Special Topics. Sérgio M. Vilas-Boas, Paula Brandão, Mónia A.R. [34] While their extract was somewhat effective, it also caused digestive problems such as gastric irritation, bleeding, diarrhea and even death when consumed in high doses. Dipali Ahuja, Michael Svärd, Åke C. Rasmuson. The melting point is, along with the boiling point, a characteristic property of every substance. In plants, it occurs naturally as a growth hormone. In addition, the morphology of salicylic acid crystals recrystallized from water differed from the other solvents. Vânia André, Inês Martins, Sílvia Quaresma, Marta Martins, M. Teresa Duarte. • Salicylic acid also exhibits a mild antiseptic effect since it is a known bacteriostatic agent. [10][11], Similar to other hydroxy acids, salicylic acid is a key ingredient in many skincare products for the treatment of seborrhoeic dermatitis, acne, psoriasis, calluses, corns, keratosis pilaris, acanthosis nigricans, ichthyosis and warts.[12].

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