I, 17th ed. Name and concentration of drug with frequency of administration, Example:  Hydrocortisone cream 2.5% apply BID, Name of drug and quantity of drug per kilogram of body weight with frequency of administration, Example:  Haloperidol 10 mcg per kg three times a day or, Haloperidol 30 mcg per kg per day in 3 divided doses, NOTE:  Again, use great CAUTION with this equivalent expression as it has been misread. What is an acceptable dose of Captopril for Tom? This is especially true for with narrow therapeutic indices and drugs used in radiopharmaceuticals. ", Initial:  Oral, 10 mcg  (0.01 mg) per kg of body weight two or three times a day, the dosage being adjusted as needed and tolerated."2. The product insert states that each Albuterol canister contains ˜ 200 inhalations. Name and quantity of drug per square meter  (m2) of body surface area with frequency of administration. What is the dose of Captopril for Milli based on normal adult dose and age? You’re supplied with a 30,000 units/500mL bag. The volume to dispense would be: Calculate the number of day's supply from the dosage regimen and the number of units dispensed - This is often required for third - party insurance claims. What is the dose of Diazepam for Jill based on the mg/kg dose given in the USP/DI? USP DI Vol. Using the references above, let’s solve some problems. First you need to convert the mg per kg into total mg by multiplying it by the patient’s weight. How many mL will you administer per dose? Tom is a 5 y. o. male patient who weighs 46 pounds. USP/DI said 1.17 - 6 mg per square meter of body surface TID - QID, Calculation of dose:  Calculating Dose ( 02080030 ). In the example, "2 . If necessary, consider switching some doses to paracetamol. Jill is a 5 y. o. female patient. Click Here for Glossary Index! The prescriber wants to give Captopril to Milli. 8. NOTE:  Again use CAUTION with this equivalent expression as it has been misread. Amount of drug per kilogram of body weight, e.g. Use the, Using the ibuprofen calculator: an example, the maximum daily limit, regardless of the weight. 2. A dose is the quantity of drug taken or given. Doctor orders 12 units/kg/hr Heparin infusion. Find the patient's weight in pounds or kilograms on the right hand side of the nomogram. Privacy Policy. 25 mg, 5 ml, 250 mg/ml. BENLYSTA is administered as an intravenous infusion and must be reconstituted and diluted prior to administration. Dosing for an infant based on the normal adult doses and "Fred's Rule" for pediatric dosing is used when we have no standard of reference. Let's assume that your child weighs 35 kg. Initial: Oral, 300 mcg (0.3 mg) per kg of body weight three times a day, the dosage being increased if necessary. (e.g. Please consult your pediatrician before administering more drugs to your child. What is the dose of Diazepam for Jill based on the quantity given in the USP/DI? What is the dose of Captopril for Milli based on the mg/kg dose given in the USP/DI? ", Oral, 10 mcg  (0.01 mg) per kg of body weight two or three times a day, the dosage being adjusted as needed and tolerated."2. 7. Body Surface Area (BSA) is based on Jill's weight and height and is read from a nomogram (nomograms for adults and children are included). If the child requires a liquid product, Cefaclor is available in a reconstitutable suspension which has a concentration of 250 mg/5 ml. Lbs / 2.2 = kg; Kg x 2.2 = lbs; Weight x dosage per weight . Gives the name and the quantity or concentration of drug with frequency of schedule of administration is a dosage regimen. In case you choose a custom version, we'll need: Our ibuprofen dosage calculator will also specify the maximum permissible doses of ibuprofen, assuming that the maximum safe dosage is 40 mg per 1 kg of body weight. What is the dose of Diazepam for Jill based on the mg/m2 , body surface area (BSA) dose given in the USP/DI? Calculate the dose of Captopril based on Tom's weight: Calculating Dose Based on Weight  ( 02080050 ), "Usual adult and children doses are given. Amount of drug per square meter of body surface (BSA), e.g. 1. Pass Assured, LLC, Pharmacy Technician Training Systems, Haloperidol 10 mcg per kg three times a day or, Haloperidol 1 mg/m2 BSA three times a day or. For patients who have an incomplete response, consideration may be given to adjusting the dosage up to 10 mg/kg IV every 8 weeks or treating as often as every 4 weeks, bearing in mind that risk of serious infections is increased at higher doses per infusion or more frequent dosing. Calcs that help predict probability of a disease, Subcategory of 'Diagnosis' designed to be very sensitive, Disease is diagnosed: prognosticate to guide treatment. Notice that in each case the doses for Captopril for Tom are similar. The latter two methods, based on the patient's body size (weight or body surface area), are often used for pediatric doses, but they are useful for adult doses for certain drugs. The number of days supply can be calculated by dividing the number of capsules dispensed by the number of capsules used per day. The recommended dosage regimen is 10 mg/kg at 2-week intervals for the first 3 doses and at 4-week intervals thereafter. Calculations, Doses and Dosage Regimens USP DI Vol. 2. Give for ten days. It is the duty of pharmacists to be knowledgeable about the limitations of using set formulas or rules for calculating pediatric doses, It is best to use dosing based on information in pharmacy reference books or package inserts. USP DI Vol. Name and quantity of drug with frequency of administration, Example:  Diazepam 2 mg three times a day or. It is the dedication of healthcare workers that will lead us through this crisis. (Two rules may be used.). Albuterol Inhaler 17 g  Use two puffs QID. So for a person who weighs 70kg, 0.5mg per kg is the same as 35mg. The answer is an infusion at = 20 mL/hr. = 75 mg = 100 mg = 125 mg = 150 mg Each Dose (based on 10 mg/kg) Max Dose Calculation kg x 10 = Clinician Select Initial mg WARNINGS DO NOT give more than 4 doses in 24-hour period. Cefaclor is to be given in two divided doses, If the child can take capsules, this would be twenty 250 mg capsules. Rockville, MD, The United States Pharmacopeial Convention, Inc. 1997, p. 543. The meaning of each variable is described in detail below. As a reference point, we will first calculate Tom's dose based on the usual pediatric mg/kg dose given in the USP/DI. at 25 mL/kg per day. Calculating milligrams per minute (mg/min) Desired mg/min x 60 min/h ----- = mL/h Medication concentration (mg/ml) Lidocaine 1 g has been added to 500 mL of D5W. USP DI Vol. Why? Let's assume you want to give this drug to the child in the form of a custom solution, of a strength 30 mg/ml. Example:  Haloperidol 1 mg/m2 BSA three times a day or, Haloperidol 3 mg per m2 per day in 3 divided doses. In this instance: 0.5mg/kg/hr x 70kg x 50ml / 250mg = 7ml/hr. The Local Anesthetic Dosing Calculator doses local anesthetics to help avoid toxic doses. The number of days supply can be calculated by dividing 200 inhalations by 8 inhalations per day = 25 days. Cefaclor 25mg/kg/day in 2 divided doses. DO NOT give ibuprofen to children under 6 months of age. Draw a straight line connecting these two points and red the BSA in m2 at the point the line intersects with the middle line. Since this prescription calls for 2 puffs four times a day, this patient will be using 8 inhalations per day. If you think your child needs more than the maximal dose, it's possible to use ibuprofen and paracetamol alternately. Type D calculations The patient weighs 130 pounds. The patient weighs 200 lbs. Again use CAUTION with this equivalent expression as it has been misread. 20 mL per kg; Weight based. You are the nurse for a 45-year-old patient who is NPO and needs to have fluids. 250mg/5ml   Take i tsp TID for one week, Therefore 5ml/dose x3 doses daily x 7 days = 105 ml. Try it for yourself and see! Once you have calculated this, the infusion rate can be worked out as in the Type B calculations. What is the dose of Captopril for Tom based of the mg/kg dose given in the USP/DI - the standard of reference? Review methods of expressing doses and dosage regimens, Learn to calculate the amount of drug product to dispense or days supply form a dosage regime. The general rules are not drug - specific and should be only used in the absence of more complete information. What is the mL/hour rate? Find the patient's height in inches or centimeters on the left hand side of  the nomogram. The Local Anesthetic Dosing Calculator doses local anesthetics to help avoid toxic doses. The patient weighs 115 lbs. Calculate the dose of Diazepam based on Jill's weight: Calculating Dose Based on Weight  ( 02080020 ). We can then compare the results. Initial:  Oral, 300 mcg (0.3 mg) per kg of body weight three times a day, the dosage being increased if necessary."2. NOTE:  The technician should use CAUTION when doses are expressed in the second way as it has been misread as 6 mg/dose to be given in 3 doses/day - 3 times a day is the intended dose! Use table below for ibuprofen infant drops or infant oral suspension (liquid). This dosage regimen is very close to that found in part a which is based on the drug - specific dosage regimen found in the USP/DI, however, the dose of Captopril for Milli based on normal adult dose and weight as given by Clark's Rule is not so successful. Jill weighs 42 pounds and is 43 inches tall. Make sure to check out the paracetamol dosage calculator as well. The prescriber wants to give Captopril to Tom. Please keep in mind that recommended single or daily dosage may be different depending on your country. Calculating the amount of drug product to dispense or days supply from a dosage regimen. The nurse needs to calculate the mL/h for the infusion pump. Cephalexin 500 mg capsules        Give i cap BID for 10 days. Rockville, MD, The United States Pharmacopeial Convention, Inc. 1997, p. 172. This ibuprofen dosage calculator, a variation of our dosage calculator, is a tool which calculates the maximum permissible ibuprofen dosage for kids. USP/DI:  "Usual adult and adolescent dose Antihypertensive: Initial:  Oral, 12.5 mg two or three times a day, the dosage being increases if necessary. Then we will calculate doses for Tom based on the age and weight rules for pediatric dosing.

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